Description
Product Characteristics:
Exonuclease with a preference for double-stranded DNA with mismatched 3' termini. May play a role in DNA repair.
Subcellular location: Nucleus
Synonyms: Three prime repair exonuclease 2, 3'-5' exonuclease TREX2, TREX2
Target Information: This gene encodes a protein with 3' exonuclease activity. Enzymes with this activity are involved in DNA replication, repair, and recombination. Similarity to an E. coli protein suggests that this enzyme may be a subunit of DNA polymerase III, which does not have intrinsic exonuclease activity